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CAN PERSISTENT HICCUPS BE A PROGRESSION MARKER IN COVID-19?

HANDAN ALAY, NAZIM DOĞAN, ZÜLAL ÖZKURT, NURAY BİLGE, FATMA KESMEZ CAN, ÖMER ARAZ

Journal of Health Sciences and Medicine - 2021;4(2):240-242

Ataturk University, School of Medicine, Department of Infectious Disease and Clinical Microbiology, Erzurum, Turkey

 

Hiccup is a reflex action that may rarely be intractable. A 55-year-old man diagnosed with COVID-19 was hospitalized to our clinic with body temperature elevation, weakness, and headache persisting for the previous three days. Persistent hiccups were present during follow-up, and progression was observed at pulmonary tomography with an increase in the numbers and dimensions of focal ground glass areas. Lymphocyte count was 920/μL, platelet count 138×103/μL, sedimentation rate 6 mm/h, ferritin 1256 ng/mL, C-reactive protein 16.8 mg/L, aspartate aminotransferase 43 U/L, alanine aminotransferase 67 U/L, and lactate dehydrogenase 326 U/L. Other potential causes of persistent hiccups were excluded. COVID-19 immune plasma and remdesivir therapy were initiated. The hiccups resolved two days after treatment, and the patient was discharged on the 11th day of follow-up. Persistent hiccups should be remembered among the symptoms that may appear during the clinical progression of COVID-19.