MERT GÖL, ALİ BALOĞLU, OĞUZHAN ALPAYDIN, AHMET KILYAR
Gynecology Obstetrics & Reproductive Medicine - 2005;11(1):49-51
Objective: To examine the value of transvaginal ultrasonography in the detection of endometrial disease in perimenopausal women with irregular uterine bleeding. Study Design: Fifty perimenopausal women with irregular uterine bleeding for at least 3 months were recruited in the study. Endometrial thickness measurement by transvaginal ultrasonography was performed in each patient. Endometrial tissue sampling was performed by dilatation and curettage. The ultrasonographic results were compared with the histological diagnosis obtained from the endometrial biopsy Results: Mean endometrial thickness was higher in patients with hyperplasia and endometrial cancer than those patients with benign histopathologic diagnoses (P<.05). The sensitivity, specificity, positive predictive value, and negative predictive value of transvaginal ultrasonography were 100%, 87.8%, 80.9%, and 100%, respectively, as determined by a cut-off level of 13 mm. Conclusions: Transvaginal sonographic examination of the endometrium is a sensitive diagnostic method for the detection of endometrial cancer and hyperplasia in perimenopausal women with irregular uterine bleeding.
